By now I think we all know that the hallmark sign of sickle cell disease is pain crisis. A sickle cell crisis is pain that can begin suddenly and last several hours or go on for days. This happens when sickled red blood cells block small blood vessels that carry blood to the bones.
Sickle cell crisis has some major features which include:
- Fatigue & Anemia
- Leg ulcers among others
- Haemolytic and;
- Bone Pain crisis